Increased Oxidative DNA Damage in Seminal Plasma of Infertile Men
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This article was originally published in a journal by OMICS Publishing Group, and the attached copy is provided by OMICS Publishing Group for the author’s benefit and for the benefit of the author’s institution, for commercial/research/educational use including without limitation use in instruction at your institution, sending it to specific colleagues that you know, and providing a copy to your institution’s administrator.
منابع مشابه
P-227: Effect of Cigarette Smoking on Seminal TAC and MDA Levels in Fertile and Infertile Men
Background: Defective sperm function is now recognized as one of the most important causes of male infertility. Lipid peroxidation (LPO) is known to cause various impairments of sperm cells and may play a major role in the etiology of male infertility. Malondialdehyde (MDA) is one of the final products of lipid peroxidation in seminal plasma. Seminal plasma possesses a rich source of different ...
متن کاملNitric Oxide Level in Seminal Plasma and Its Relation with Sperm DNA Damages
Evidence supports the involvement of nitric oxide (NO) in a Varity of male reproductive processes such as spermatogenesis, spermiogenesis, sperm motion, sperm metabolism and sperm capacitation. However, Low concentration of NO is essential in biology and physiology of spermatozoa, but high amounts of NO is toxic and has negative effects on sperm functions. On the other hand, it is established t...
متن کاملOxidative DNA Damage to Sperm Cells and Peripheral Blood Leukocytes in Infertile Men
BACKGROUND Oxidative DNA damage is associated with male infertility. The aim of this study was to evaluate the oxidative DNA damage of sperm cells and blood leukocytes and to determine the levels of MDA and NO levels in seminal and blood plasma of idiopathic infertile men. MATERIAL AND METHODS The study enrolled 52 patients, including 30 infertile and 22 fertile men. MDA, NO, and 8-OHdG/106dG w...
متن کاملP-79: The Correlation between Nitric Oxide Levels in Seminal Plasma with Human Sperm Parameters
Background: Defective sperm quality is a significant cause of infertility in men. It is known that nitric oxide (NO) is a highly reactive free radical gas which has a dual function, being both a cytotoxic and necessary molecule for normal sperm production. Materials and Methods: To investigate correlation between NO levels with sperm parameters, a case-control study were designed with total of ...
متن کاملThe influence of oxidative damage on viscosity of seminal fluid in infertile men.
Increased oxidative damage has been suggested to play an important role in the viscosity changes of blood. However, changes in levels of oxidative damage products in semen and their relationship to seminal fluid viscosity are unknown. The aim of our study was to investigate whether oxidative damage was associated with seminal plasma viscosity in infertile subjects. The levels of malondialdehyde...
متن کاملP-3: Study of Relationship between Nitric Oxide and DNA Oxidative Marker in Semen of Diabetic Men
Background: The incidence of diabetes mellitus is rapidly increasing in the world. One of the complications of diabetes includes disturbance of the reproductive tract, such as infertility, erectile dysfunction, and endocrine disturbances. Nitric oxide (NO) is a free radical produced by most of cells including the human male and female reproductive tracts. NO has a dual role where low concentrat...
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تاریخ انتشار 2014